I have had few crashes and slowdown issues with TDM 1.07. Specs i5 2500k GTX 580 8GB W7 64bit Tears of St. Lucia crashed when I finished the mission. Loading the save and finishing the mission results in crash. A Score to Settle crashed somewhere midway through the mission. I saved just few seconds before this so the save resulted in same result every time. And the random slowdowns, the game just starts to lag badly and then really badly. Saving and loading fixes it. Actually they aren't that random, they happen sometimes after a while I started a mission, Alberic's Curse and A Score to Settle had this issue so far. Maybe others. I'm running 1680x1050 res, full details, 4xAA. In attemp to fix these issues I dropped to 2xAA, changed nvidia setting "Also set "Multi-display/Mixed GPU acceleration" to "Single display performance mode"" and enabled compression in doomconfig in darkmod folder. Compression lowers quality so is it really necessary? I didn't Disable Nvidia "Threaded Optimizations" because it wouldn't let me do that specifically to doom3. Only global setting and then I would have to change that every time I play TDM and other games. Not a big deal if it guarentees fixes. After those changes I restarted A Score to Settle and finished without crash but had slowdown.