I was able to install, launch, and watch the opening videos of TDM 2.10 on a Pi 4b via Box86 by setting the environment variable MESA_GL_VERSION_OVERRIDE=3.3 first. However, it froze after a frame or two of gameplay. I haven't tried to debug that yet. Note that TDM 2.08 and earlier use GL3.1+extensions (but still probably require 3.3-compliant hardware unless you're up for some hacking) and 1.08 and earlier are judt Doom 3 mods (but incompatible with Dhewm3).